Against The Grain Brewery & Smokehouse is located in the southeast corner of Louisville Slugger Field at the corner of Jackson and Main Street. It is a former train station that features beautifully ornate industrial architecture, lending to the beauty of the dining room and brewhouse. Inside you will find one of the nations only operational, Victorian styled and 3 story ‘showpiece’ brewhouses. The copper clad 15 barrel brewhouse is complemented by eclectic pieces of art produced by Louisvillian artists.
As of Friday, May 22, 2020, Against the Grain Brewery & Smokehouse is open for dine-in service on our patio! For more info on our reopening click here.
We are still offering carry-out service for both food and beer!
For carry-out or curbside service, please call 502-515-0174 or 502-515-0175.
Sunday - Saturday | 4:00 PM - 10:00 PM
401 East Main Street Louisville, KY 40202
Orders take 15-20 minutes and guests should park in front of Against the Grain Brewery and Smokehouse on Main Street with flashers on for free parking!
Don’t forget this includes carry-out and curbside service on cocktails and packaged beer! Must be 21+ to order beer. We check IDs upon pick-up.
Grandma's Purple Nipple
Champagne Aged Basque Salts
Bottle & Gift Shop
At our Bottle & Gift Shop, you can stay and sip or buy and dip! We have a selection of Against the Gain beers you already love and some that are exclusive to our shop in package and on draft. You’ll also find a wide variety of Against the Grain merchandise, as well as beers from some of our brewery friends like Stillwater and Marz.